Successful treatment with long-acting injectable aripiprazole monohydrate for two patients with dual diagnosis - substance use disorder and psychotic disorder

In recent years, the rate of substance-induced psychotic disorder (SIPD) has been gradually increasing. Non-compliance with treatment and substance craving are serious problems in SIPD. Novel depot antipsychotic treatments, such as long-acting injectable aripiprazole monohydrate 400 mg (LAIAM) reported to improve compliance functionality disorders. However, number studies showing efficacy LAIAM patients dual diagnosis is limited. this paper, we present two cases. The first case was diagnosed SIPD other a past history profound use disorder. cases showed both clinical functional improvement at 1-year follow-up after initiation treatment. These reports suggest that might be an effective safe option reduce craving.